Pancreatic endocrine tumours: evidence for a tumour suppressor pathogenesis and for a tumour suppressor gene on chromosome 17p

1998 ◽  
Vol 186 (1) ◽  
pp. 41-50 ◽  
Author(s):  
Stefania Beghelli ◽  
Giuseppe Pelosi ◽  
Giuseppe Zamboni ◽  
Massimo Falconi ◽  
Calogero Iacono ◽  
...  
Keyword(s):  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Endocrine Tumours ◽  
Pancreatic Endocrine Tumours

Analysis of the retinoblastoma tumour suppressor gene in pancreatic endocrine tumours

1997 ◽  
Vol 47 (5) ◽  
pp. 523-528 ◽  
Author(s):  
Daniel C. Chung ◽  
Alison P. Smith ◽  
David N. Louis ◽  
Fiona Graeme-Cook ◽  
Andrew L. Warshaw ◽  
...  
Keyword(s):  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Endocrine Tumours ◽  
Pancreatic Endocrine Tumours ◽  
Retinoblastoma Tumour Suppressor

scholarly journals 15 YEARS OF PARAGANGLIOMA: The association of pituitary adenomas and phaeochromocytomas or paragangliomas

2015 ◽  
Vol 22 (4) ◽  
pp. T105-T122 ◽  
Author(s):  
Samuel M O'Toole ◽  
Judit Dénes ◽  
Mercedes Robledo ◽  
Constantine A Stratakis ◽  
Márta Korbonits
Keyword(s):  
Succinate Dehydrogenase ◽  
Molecular Genetics ◽  
Pituitary Adenomas ◽  
Rare Event ◽  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Endocrine Tumours ◽  
Pituitary Tumorigenesis ◽  
Predisposing Genes

The combination of pituitary adenomas (PA) and phaeochromocytomas (phaeo) or paragangliomas (PGL) is a rare event. Although these endocrine tumours may occur together by coincidence, there is mounting evidence that, in at least some cases, classical phaeo/PGL-predisposing genes may also play a role in pituitary tumorigenesis. A new condition that we termed ‘3Pas’ for the association of PA with phaeo and/or PGL was recently described in patients with succinate dehydrogenase mutations and PAs. It should also be noted that the classical tumour suppressor gene,MEN1that is the archetype of the PA-predisposing genes, is also rarely associated with phaeos in both mice and humans with MEN1 defects. In this report, we review the data leading to the discovery of 3PAs, other associations linking PAs with phaeos and/or PGLs, and the corresponding clinical and molecular genetics.

Mutational analysis of PPARG as a candidate tumour suppressor gene in enteropancreatic endocrine tumours

2005 ◽  
Vol 62 (5) ◽  
pp. 603-606 ◽  
Author(s):  
Jessica Costa-Guda ◽  
Evan D. Rosen ◽  
Robert T. Jensen ◽  
Daniel C. Chung ◽  
Andrew Arnold
Keyword(s):  
Mutational Analysis ◽  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Endocrine Tumours ◽  
Candidate Tumour Suppressor

tumour suppressor gene and the tobacco industry

The Lancet ◽  
2005 ◽  
Vol 365 (9464) ◽  
pp. 1026-1027
Author(s):  
A BITTON ◽  
M NEUMAN ◽  
J BARNOYA ◽  
S GLANTZ
Keyword(s):  
Tobacco Industry ◽  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor

FOXL2 in adult‐type granulosa cell tumour of the ovary: oncogene or tumour suppressor gene?

2021 ◽  
Author(s):  
Jessica A. Pilsworth ◽  
Anne‐Laure Todeschini ◽  
Samantha J. Neilson ◽  
Dawn R. Cochrane ◽  
Daniel Lai ◽  
...  
Keyword(s):  
Granulosa Cell ◽  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Cell Tumour ◽  
Granulosa Cell Tumour ◽  
Adult Type
Sign in / Sign up

Export Citation Format

Share Document